Station 4 of 13 · Molecule · the record
Hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC)
Hydroxyisohexyl 3-cyclohexene carboxaldehyde, HICC, was a muguet material of the twentieth century; EU law now prohibits it in cosmetic products.
From 23 August 2019 cosmetic products containing it could not be placed on the EU market. IFRA’s Standard, published in 2020, restricts it. Its identity is PubChem’s.
The record
Each field carries its evidence: open a chip for the source, the quoted words and the confidence. A field with nothing behind it says so and stays empty.
- Name
- hydroxyisohexyl 3-cyclohexene carboxaldehyde (HICC)
documented
79 3 and 4-(4-Hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde Hydroxyisohexyl 3-cyclohexene carboxaldehyde 51414-25-6/31906-04-4
EU-2009-1223 · Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November · read 2026-09-30
the INCI name EU law uses; IFRA calls it HMPCC; PubChem’s title for CID 91604 is "Liral", a trade name
confidence A
- CAS
- 31906-04-4
documented
31906-04-4
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
among the CID’s PubChem synonyms, and PubChem resolves it back to this CID
confidence A
- PubChem CID
- 91604
documented
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
confidence A
- Formula
- C13H22O2
documented
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
confidence A
- Molecular weight
- 210.31
documented
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
g/mol, as PubChem states it
confidence A
- IUPAC name
- 4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde
documented
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
confidence A
- SMILES
- CC(C)(CCCC1=CCC(CC1)C=O)O
documented
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
confidence A
- InChIKey
- ORMHZBNNECIKOH-UHFFFAOYSA-N
documented
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
confidence A
- Odour threshold
- withheld: not on record
withheld
no odour-threshold source in the repository
- Descriptors
- not on record
not on record
no descriptor on record: no house wording on a data file, no descriptor source filed
- Volatility class
- not on record
not on record
no volatility class on record for hicc (the simulator’s data has no entry)
- Regulation
- IFRA Standard: 3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC)
- Regulation (EC) No 1223/2009 on cosmetic products
- Regulation (EU) 2017/1410 (HICC, atranol and chloroatranol prohibited)
documented
IFRA-044, EU-2009-1223, EU-2017-1410: each record above quotes its entry.
- 3D structure
- PubChem computed 3D conformer · 37 atoms, 37 bonds
modeled
PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene- · read 2026-09-30
PubChem’s computed 3D conformer (the 3D SDF record): a model, drawn schematically, not an experimental structure
confidence A
- Occurs in
- In teaching accords
Sources
- PUBCHEM-91604 · PubChem Compound Summary for CID 91604, Liral (4-(4-hydroxy-4-methylpentyl)cyclohex-3-ene-1-carbaldehyde). National Center for Biotechnology Information (NCBI), U.S. National Library of Medicine; live database, read 2026-09-30 through the PUG REST endpoints (no account): https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/name/31906-04-4/cids/JSON · https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/91604/property/MolecularFormula,MolecularWeight,IUPACName,Title,SMILES,InChIKey/JSON · https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/91604/synonyms/JSON · https://pubchem.ncbi.nlm.nih.gov/rest/pug/compound/cid/91604/SDF?record_type=3d. pubchem.ncbi.nlm.nih.gov/compound/91604 · read 2026-09-30 · PubChem data are provided by NCBI (public-domain data; cite PubChem); the computed conformer is PubChem-generated. The raw responses are filed as fetched (the house’s records; the house’s review log the house’s records).
- IFRA-044 · International Fragrance Association (IFRA). IFRA Standard: 3 and 4-(4-Hydroxy-4-methylpentyl)-3-cyclohexene-1-carboxaldehyde (HMPCC), Amendment 49 (2020). Geneva: IFRA Standards Library. d3t14p1xronwr0.cloudfront.net/docs/standards/IFR… · read 2026-09-30 · published by IFRA; no reuse licence stated; quoted
- EU-2009-1223 · Regulation (EC) No 1223/2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products (recast). OJ L 342, 22.12.2009, p. 59. eur-lex.europa.eu/eli/reg/2009/1223/oj · read 2026-09-30 · EU legislation; reuse terms not re-read (UNVERIFIED); quoted
- EU-2017-1410 · Commission Regulation (EU) 2017/1410 of 2 August 2017 amending Annexes II and III to Regulation (EC) No 1223/2009. OJ L 202, 3.8.2017, p. 1. eur-lex.europa.eu/eli/reg/2017/1410/oj · read 2026-09-30 · EU legislation; reuse terms not re-read (UNVERIFIED); quoted
These records are published under CC BY 4.0.
this record as data: /data/molecule/hicc.json · version 1 · updated 2026-09-30 · confidence A